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How Does Seasonal Flu Differ from Pandemic Flu?
 
SEASONAL FLU PANDEMIC FLU
Outbreaks follow predictable seasonal patterns; occurs annually, usually in winter, in temperate climates

Usually some immunity built up from previous exposure

Occurs rarely (three times in 20th century - last in 1968)

No previous exposure; little or no pre-existing immunity

Healthy adults usually not at risk for serious complications (the very young, the elderly and those with certain underlying health conditions at increased risk for serious complications) Healthy people may be at increased risk for serious complications
Health systems can usually meet public and patient needs Health systems may be overwhelmed
Vaccine developed based on known virus strains and available for annual flu season Vaccine probably would not be available in the early stages of a pandemic
Adequate supplies of antivirals are usually available Effective antivirals may be in limited supply
Average U.S. deaths approximately 36,000/yr Number of deaths could be quite high (e.g., U.S. 1918 death toll approximately 500,000)
Symptoms: fever, cough, runny nose, muscle pain. Deaths often caused by complications, such as pneumonia. Symptoms may be more severe and complications more frequent
Generally causes modest impact on society (e.g., some school closing, encouragement of people who are sick to stay home) May cause major impact on society (e.g. widespread restrictions on travel, closings of schools and businesses, cancellation of large public gatherings)
Manageable impact on domestic and world economy

Potential for severe impact on domestic and world economy

For additional information visit: www.pandemicflu.gov

From the United States Department of Health and Human Services